Which treatment is NOT appropriate for ITP?

In the management of Immune Thrombocytopenic Purpura (ITP), anticoagulants are not appropriate treatment options. The underlying problem in ITP is a low platelet count due to the immune system mistakenly destroying platelets. Introducing anticoagulants, which are intended to prevent clotting, can exacerbate bleeding risks associated with an already low platelet count.

In contrast, IVIG (intravenous immunoglobulin) can be used in cases where rapid increase in platelet count is necessary, such as before surgery or serious invasive procedures. Corticosteroids are frequently employed to reduce immune-mediated platelet destruction. Splenectomy may be considered in chronic cases where other treatments fail, as the spleen is responsible for the destruction of platelets in ITP. Each of these treatments addresses the disease process by either increasing platelet levels or reducing their destruction, making them suitable for managing ITP.