Which symptoms are indicative of hypokalemia?

Muscular weakness and fatigue are hallmark symptoms of hypokalemia due to the role of potassium in muscle function and nerve conduction. Potassium is essential for maintaining normal muscle contractions and electrical activity in nerves. When potassium levels are low, it can lead to impaired muscle function, resulting in weakness and fatigue. This can manifest in various ways, such as decreased muscle strength, difficulty with coordination, or general tiredness.

In the context of hypokalemia, these symptoms stem from the disruption of the resting membrane potential of muscle cells, which can lead to decreased excitability and contractility. While other symptoms related to hypokalemia, such as cardiac arrhythmias, may also occur, the muscular weakness and fatigue are often the first and most noticeable signs that prompt further investigation into potassium levels.