Which of the following treatments is effective for managing symptoms of serotonin syndrome?

Dantrolene is effective in managing symptoms of serotonin syndrome, particularly when the syndrome is severe and associated with hyperthermia or significant muscular rigidity. Serotonin syndrome is a potentially life-threatening condition resulting from excessive serotonin activity in the central nervous system, often due to medication interactions or overdose.

Dantrolene works by acting directly on the skeletal muscle to reduce rigidity and hyperthermia by inhibiting calcium release from the sarcoplasmic reticulum. This mechanism is particularly helpful in the context of serotonin syndrome, where muscle rigidity and increased body temperature can pose significant risks to the patient.

In this context, while activated charcoal is used in certain situations of overdose to reduce the absorption of medications in the gastrointestinal tract, it is not an effective treatment for serotonin syndrome itself. Haloperidol, an antipsychotic, has sedative properties but doesn't address the core dysregulation of serotonin. Metoclopramide, a medication primarily used to treat nausea and gastroparesis, is not applicable for managing serotonin syndrome symptoms directly. Thus, dantrolene stands out as a specific treatment aimed at the symptoms associated with serotonin syndrome.