Which medication is often used at the onset of a migraine for quick relief?

Sumatriptan is often utilized at the onset of a migraine for quick relief because it belongs to the class of medications known as triptans, which are specifically designed for the rapid treatment of acute migraine attacks. Triptans work by agonizing serotonin receptors in the brain, leading to vasoconstriction of cranial blood vessels and blocking the release of pro-inflammatory neuropeptides. This action helps to alleviate the headache and associated migraine symptoms, such as nausea and sensitivity to light or sound.

While ibuprofen, acetaminophen, and caffeine can provide relief for some individuals, they are not as targeted or effective as sumatriptan for treating moderate to severe migraine attacks. Ibuprofen and acetaminophen are both non-opioid analgesics that may reduce pain but do not address the underlying pathophysiology of migraines. Caffeine is sometimes included in various headache treatments and can enhance the effect of pain relievers, but it is not a standalone or primary treatment for migraines. Therefore, sumatriptan is recognized as a first-line medication for acute migraine relief, providing faster and more effective management of the condition.