What medications are typically used to treat thyroid crisis?

In the context of treating a thyroid crisis, also known as thyroid storm, a combination of medications is essential to manage the hypermetabolic state effectively and address the underlying hyperthyroidism.

The correct answer includes propanolol and hydrocortisone, which play crucial roles in the management of thyroid storm. Propranolol is a non-selective beta-blocker that helps to control symptoms such as tachycardia, hypertension, and palpitations by antagonizing beta-adrenergic receptors, thereby reducing the effects of elevated thyroid hormones on the cardiovascular system. Hydrocortisone, a corticosteroid, is used to help combat the stress response, reduce inflammation, and also potentially inhibit the peripheral conversion of T4 to the more active T3, aiding in the reduction of thyroid hormone levels.

The addition of PTU (propylthiouracil) or methimazole in this context is also relevant because these medications inhibit thyroid hormone synthesis and are vital in reducing the overall production of thyroid hormones. However, the immediate management of the crisis often prioritizes the use of beta-blockers like propranolol and corticosteroids due to their rapid effects on symptom relief and stabilization.

Therefore, the combination of PTU, methimazole