What condition is commonly associated with adrenal tumors and chronic administration of glucocorticoids?

Cushing's syndrome is commonly associated with adrenal tumors and chronic administration of glucocorticoids because it results from excessive levels of cortisol in the body. Adrenal tumors, particularly adrenal adenomas or carcinomas, can produce cortisol independently of the normal regulatory mechanisms, leading to an overproduction of this hormone. Similarly, chronic administration of glucocorticoids as part of treatment for various conditions can lead to Cushing's syndrome due to the exogenous sources of cortisol.

This condition is characterized by a range of symptoms including weight gain, hypertension, hyperglycemia, and specific changes in fat distribution, such as central obesity and facial rounding. The connection with adrenal tumors comes from their role in directly secreting cortisol, while chronic glucocorticoid use mimics excess cortisol levels, leading to similar clinical features.

The other options are less relevant in this context. Hypothyroidism, Graves' disease, and thyroiditis are primarily related to disorders of the thyroid gland, rather than the adrenal glands or the effects of cortisol. Thus, Cushing's syndrome emerges as the defining condition linked to both adrenal tumors and glucocorticoid therapy.