Fatigue and muscle weakness are common manifestations of which condition?

Fatigue and muscle weakness are indeed common manifestations of hypercalcemia, which is characterized by elevated levels of calcium in the blood. When calcium levels are high, it can disrupt normal neuromuscular function, leading to symptoms such as muscle weakness, lethargy, and fatigue. This occurs because excessive calcium can interfere with the excitability of nerve and muscle cells, resulting in overall decreased muscle tone and energy levels.

In the context of hypercalcemia, the condition can result from various causes, including primary hyperparathyroidism, malignancies, or excessive calcium supplementation, which can all lead to these debilitating symptoms. Identifying hypercalcemia as the root cause of fatigue and muscle weakness is crucial because it requires a specific treatment approach, such as rehydration, bisphosphonates, or addressing the underlying causes.